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ALK inhibitor 2

CAS No. 761438-38-4

ALK inhibitor 2 ( ALK inhibitor 2; MDK-8384; MDK 8384 )

Catalog No. M19086 CAS No. 761438-38-4

ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 149 Get Quote
5MG 228 Get Quote
10MG 320 Get Quote
25MG 530 Get Quote
50MG 758 Get Quote
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Biological Information

  • Product Name
    ALK inhibitor 2
  • Note
    Research use only, not for human use.
  • Brief Description
    ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.
  • Description
    MDK-8384, also known as ALK inhibitor 2, is a potent and selective ALK inhibitor. MDK-8384 has CAS#761438-38-4. MDK-8384 was reported in J Med Chem. 2013;56(14):5675-90.
  • Synonyms
    ALK inhibitor 2; MDK-8384; MDK 8384
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ALK
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    761438-38-4
  • Formula Weight
    518.03
  • Molecular Formula
    C23H28ClN7O3S
  • Purity
    98%
  • Solubility
    DMSO : 50 mg/mL 96.52 mM;H2O : < 0.1 mg/mL
  • SMILES
    c1cc(c(cc1)Nc1c(cnc(n1)Nc1c(cc(cc1)N1CCN(CC1)C)OC)Cl)S(=O)(=O)NC
  • Chemical Name
    2-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. A Dose Finding Study With Oral LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase (ALK).
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